Protective effects of hesperetin on lipopolysaccharide-induced acute lung injury in a rat model
نویسندگان
چکیده
منابع مشابه
Time-dependent changes of autophagy and apoptosis in lipopolysaccharide-induced rat acute lung injury
Objective(s): Abnormal lung cell death including autophagy and apoptosis is the central feature in acute lung injury (ALI). To identify the cellular mechanisms and the chronology by which different types of lung cell death are activated during lipopolysaccharide (LPS)-induced ALI, we decided to evaluate autophagy (by LC3-II and autophagosome) and apoptosis (by caspase-3) at different time point...
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Objective. The aim of this research is to evaluate the protective effects of methane-rich saline (MS) on lipopolysaccharide- (LPS-) induced acute lung injury (ALI) and investigate its potential antioxidative, anti-inflammatory, and antiapoptotic activities. Methods. LPS-induced (20 mg/kg) ALI rats were injected with MS (2 ml/kg and 20 ml/kg) before the initiation of LPS induction. Survival rate...
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ژورنال
عنوان ژورنال: The Turkish Journal of Thoracic and Cardiovascular Surgery
سال: 2020
ISSN: 1301-5680,2149-8156
DOI: 10.5606/tgkdc.dergisi.2020.18816